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Liver Disease | GileadPro

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Liver Disease

For over 30 years, Gilead has been trasforming the management of Liver Disease through innovative medicines, collaboration with the Liver community, and an unwavering commitment to patients.
Learn more about our focused Liver Disease therapeutic areas

Therapeutic Areas

HCV (Hepatitis C virus)

Innovative antiviral therapies have significantly improved the cure rates for HCV, transforming it from a chronic, life-threatening condition into a curable disease for many patients.1

Find out more about hepatitis C and ongoing efforts to achieve elimination in the UK.

HDV (Hepatitis D virus)

Chronic HDV causes the most severe form of viral hepatitis and is often underdiagnosed. It can have mortality rates as high as 50% within five years for people with cirrhosis.2

Find out more about hepatitis D and the potential impact it may have on your patients.

PBC (Primary Biliary Cholangitis)

PBC is a chronic autoimmune liver disease that slowly damages the bile ducts, potentially leading to liver failure if untreated.3

Find out more about approaches and perspectives to PBC diagnosis, management and treatment.

Learn more about our Liver Disease treatment options

Our Medicines

Sofosbuvir/Velpatasvir Gilead

Sofosbuvir/Velpatasvir Gilead is indicated for the treatment of chronic hepatitis C virus (HCV) infection in patients 3 years of age and older.4

Ledipasvir/Sofosbuvir Gilead

Ledipasvir/Sofosbuvir Gilead is indicated for the treatment of chronic hepatitis C (CHC) in adult and paediatric patients aged 3 years and above.5

Please see the SmPC for hepatitis C virus (HCV) genotype-specific activity.

Sofosbuvir/Velpatasvir/ Voxilaprevir Gilead

Sofosbuvir/Velpatasvir/Voxilaprevir Gilead is indicated for the treatment of chronic hepatitis C virus (HCV) infection in patients aged 12 years and older and weighing at least 30 kg.6

Hepcludex®▼ (bulevirtide)

Hepcludex® is indicated for the treatment of chronic hepatitis delta virus (HDV) infection in plasma (or serum) HDV-RNA positive adult and paediatric patients 3 years of age and older weighing at least 10 kg with compensated liver disease.7

LIVDELZI®▼ (seladelpar)

LIVDELZI® has received conditional marketing authorisation for the treatment of primary biliary cholangitis, including pruritus, in adults in combination with ursodeoxycholic acid (UDCA) who have an inadequate response to UDCA alone, or as monotherapy in those unable to tolerate UDCA.8

On Demand and Resources

On Demand and Resources

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References
  • 1. UK HSA, 12 March 2025. Hepatitis C in England 2024. Available at https://www.gov.uk/government/publications/hepatitis-c-in-the-uk/hepatitis-c-in-england-2024. Accessed January 2026.
  • 2. Koh C, et al. Pathogenesis of and New Therapies for Hepatitis D. Gastroenterol 2018;156(2):461–476.e1.
  • 3. NHS. Overview – Primary biliary cholangitis (primary biliary cirrhosis). Available at: https://www.nhs.uk/conditions/primary-biliary-cholangitis-pbc/. Accessed January 2026.
  • 4. UK Sofosbuvir/Velpatasvir Gilead Summary of Product Characteristics. https://www.emcpi.com/pi/32177 Accessed January 2026.
  • 5. UK Ledipasvir/Sofosbuvir Gilead Summary of Product Characteristics. https://www.emcpi.com/pi/38293 Accessed January 2026.
  • 6. UK Sofosbuvir/Velpatasvir/Voxilaprevir Gilead Summary of Product Characteristics. https://www.emcpi.com/pi/33858 Accessed January 2026.
  • 7. UK Hepcludex® (bulevirtide) Summary of Product Characteristics. https://www.emcpi.com/pi/41295 Accessed January 2026.
  • 8. UK LIVDELZI® (seladelpar) Summary of Product Characteristics. https://www.emcpi.com/pi/103133 Accessed January 2026.

UKI-UNB-1431 | January 2026